Protein Details: Gap junction beta-4 protein

Protein ID

ICDB_Pro_0506

Protein Name

Gap junction beta-4 protein

Gene Name

Gjb4; Cxn-30.3

Organism

Rattus norvegicus (Rat)

Length

265 amino acids

AlphaFoldDB

AF-P36380-F1-model_v4.pdb

Function

Sequence

MNWGFLQGILSGVNKYSTALGRIWLSVVFIFRVLVYVVAAEEVWDDEQKDFICNTKQPGCPNVCYDEFFPVSHVRLWALQLILVTCPSLLVVMHVAYREERERKHRLKHGPDAPALYSNLSKKRGGLWWTYLLSLIFKAAVDSGFLYIFHCIYKDYDMPRVVACSVQPCPHTVDCYISRPTEKKVFTYFMVVTAAICILLNLSEVAYLVGKRCMEVFRPRRQKTSRRHQLPDTCPPYVISKGHPQDESTVLTKAGMATVDAGVYP

PDB Structures

Ligand Binding

1. DICL_CP

2. DICL_Pep

Binding Site

Disease

Location

Detected in adult heart; kidney; skin and cochlea; where it is detected in spiral ganglion; stria vascularis; spiral limbus and spiral ligament (at protein level)

DOI ID

10.1006/excr.1994.1194; 10.1016/j.heares.2010.02.008

RefSeq

NP_446436.1